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The CCR5Δ32 allele is not a major predisposing factor for severe H1N1pdm09 infection
BACKGROUND: Host genetic factors are thought to modulated the severity of disease caused by infection with the 2009 H1N1 pandemic influenza virus (H1N1pdm09). The human CCR5 gene encodes a cytokine receptor important for cell-mediated immune response against H1N1pdm09. A 32-bp polymorphic deletion i...
Autores principales: | Sironi, Manuela, Cagliani, Rachele, Pontremoli, Chiara, Rossi, Marianna, Migliorino, Guglielmo, Clerici, Mario, Gori, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132245/ https://www.ncbi.nlm.nih.gov/pubmed/25100510 http://dx.doi.org/10.1186/1756-0500-7-504 |
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