Redox signaling via the molecular chaperone BiP protects cells against endoplasmic reticulum-derived oxidative stress

Oxidative protein folding in the endoplasmic reticulum (ER) has emerged as a potentially significant source of cellular reactive oxygen species (ROS). Recent studies suggest that levels of ROS generated as a byproduct of oxidative folding rival those produced by mitochondrial respiration. Mechanisms...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Pareja, Kristeen A, Kaiser, Chris A, Sevier, Carolyn S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132286/
https://www.ncbi.nlm.nih.gov/pubmed/25053742
http://dx.doi.org/10.7554/eLife.03496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132286/
https://www.ncbi.nlm.nih.gov/pubmed/25053742
http://dx.doi.org/10.7554/eLife.03496

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