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Redox signaling via the molecular chaperone BiP protects cells against endoplasmic reticulum-derived oxidative stress
Oxidative protein folding in the endoplasmic reticulum (ER) has emerged as a potentially significant source of cellular reactive oxygen species (ROS). Recent studies suggest that levels of ROS generated as a byproduct of oxidative folding rival those produced by mitochondrial respiration. Mechanisms...
Autores principales: | Wang, Jie, Pareja, Kristeen A, Kaiser, Chris A, Sevier, Carolyn S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132286/ https://www.ncbi.nlm.nih.gov/pubmed/25053742 http://dx.doi.org/10.7554/eLife.03496 |
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