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Regulation and Role of EZH2 in Cancer

Polycomb repressive complex 2 (PRC2) is the epigenetic regulator that induces histone H3 lysine 27 methylation (H3K27me3) and silences specific gene transcription. Enhancer of zeste homolog 2 (EZH2) is an enzymatic subunit of PRC2, and evidence shows that EZH2 plays an essential role in cancer initi...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hirohito, Hung, Mien-Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132442/
https://www.ncbi.nlm.nih.gov/pubmed/25038756
http://dx.doi.org/10.4143/crt.2014.46.3.209