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Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis

Diagnosis, stratification and monitoring of disease progression in amyotrophic lateral sclerosis currently rely on clinical history and examination. The phenotypic heterogeneity of amyotrophic lateral sclerosis, including extramotor cognitive impairments is now well recognized. Candidate biomarkers...

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Detalles Bibliográficos
Autores principales: Menke, Ricarda A. L., Körner, Sonja, Filippini, Nicola, Douaud, Gwenaëlle, Knight, Steven, Talbot, Kevin, Turner, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132644/
https://www.ncbi.nlm.nih.gov/pubmed/24951638
http://dx.doi.org/10.1093/brain/awu162