Cargando…

A data-driven model of biomarker changes in sporadic Alzheimer's disease

We demonstrate the use of a probabilistic generative model to explore the biomarker changes occurring as Alzheimer’s disease develops and progresses. We enhanced the recently introduced event-based model for use with a multi-modal sporadic disease data set. This allows us to determine the sequence i...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Alexandra L., Oxtoby, Neil P., Daga, Pankaj, Cash, David M., Fox, Nick C., Ourselin, Sebastien, Schott, Jonathan M., Alexander, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132648/
https://www.ncbi.nlm.nih.gov/pubmed/25012224
http://dx.doi.org/10.1093/brain/awu176