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A data-driven model of biomarker changes in sporadic Alzheimer's disease

We demonstrate the use of a probabilistic generative model to explore the biomarker changes occurring as Alzheimer’s disease develops and progresses. We enhanced the recently introduced event-based model for use with a multi-modal sporadic disease data set. This allows us to determine the sequence i...

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Detalles Bibliográficos
Autores principales:	Young, Alexandra L., Oxtoby, Neil P., Daga, Pankaj, Cash, David M., Fox, Nick C., Ourselin, Sebastien, Schott, Jonathan M., Alexander, Daniel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132648/ https://www.ncbi.nlm.nih.gov/pubmed/25012224 http://dx.doi.org/10.1093/brain/awu176

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