MYC is essential for the formation and maintenance of germinal centers

Germinal centers (GC) are sites of intense B cell proliferation, central for T cell dependent antibody responses. However, the role of MYC, a key cell cycle regulator, in this process has been questioned. Here, we identified MYC positive B cell subpopulations in immature and mature GCs, and show thr...

Descripción completa

Detalles Bibliográficos
Autores principales: Calado, Dinis Pedro, Sasaki, Yoshiteru, Godinho, Susana A., Pellerin, Alex, Köchert, Karl, Sleckman, Barry P., de Alborán, Ignacio Moreno, Janz, Martin, Rodig, Scott, Rajewsky, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132664/
https://www.ncbi.nlm.nih.gov/pubmed/23001146
http://dx.doi.org/10.1038/ni.2418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132664/
https://www.ncbi.nlm.nih.gov/pubmed/23001146
http://dx.doi.org/10.1038/ni.2418

Ejemplares similares