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Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations

Next-generation sequencing (NGS) technologies enable new insights into the diversity of virus populations within their hosts. Diversity estimation is currently restricted to single-nucleotide variants or to local fragments of no more than a few hundred nucleotides defined by the length of sequence r...

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Detalles Bibliográficos
Autores principales: Giallonardo, Francesca Di, Töpfer, Armin, Rey, Melanie, Prabhakaran, Sandhya, Duport, Yannick, Leemann, Christine, Schmutz, Stefan, Campbell, Nottania K., Joos, Beda, Lecca, Maria Rita, Patrignani, Andrea, Däumer, Martin, Beisel, Christian, Rusert, Peter, Trkola, Alexandra, Günthard, Huldrych F., Roth, Volker, Beerenwinkel, Niko, Metzner, Karin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132706/
https://www.ncbi.nlm.nih.gov/pubmed/24972832
http://dx.doi.org/10.1093/nar/gku537