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Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations
Next-generation sequencing (NGS) technologies enable new insights into the diversity of virus populations within their hosts. Diversity estimation is currently restricted to single-nucleotide variants or to local fragments of no more than a few hundred nucleotides defined by the length of sequence r...
Autores principales: | Giallonardo, Francesca Di, Töpfer, Armin, Rey, Melanie, Prabhakaran, Sandhya, Duport, Yannick, Leemann, Christine, Schmutz, Stefan, Campbell, Nottania K., Joos, Beda, Lecca, Maria Rita, Patrignani, Andrea, Däumer, Martin, Beisel, Christian, Rusert, Peter, Trkola, Alexandra, Günthard, Huldrych F., Roth, Volker, Beerenwinkel, Niko, Metzner, Karin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132706/ https://www.ncbi.nlm.nih.gov/pubmed/24972832 http://dx.doi.org/10.1093/nar/gku537 |
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