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Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer
The mechanism for generating double minutes chromosomes (dmin) and homogeneously staining regions (hsr) in cancer is still poorly understood. Through an integrated approach combining next-generation sequencing, single nucleotide polymorphism array, fluorescent in situ hybridization and polymerase ch...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132716/ https://www.ncbi.nlm.nih.gov/pubmed/25034695 http://dx.doi.org/10.1093/nar/gku590 |