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Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer

The mechanism for generating double minutes chromosomes (dmin) and homogeneously staining regions (hsr) in cancer is still poorly understood. Through an integrated approach combining next-generation sequencing, single nucleotide polymorphism array, fluorescent in situ hybridization and polymerase ch...

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Detalles Bibliográficos
Autores principales:	L'Abbate, Alberto, Macchia, Gemma, D'Addabbo, Pietro, Lonoce, Angelo, Tolomeo, Doron, Trombetta, Domenico, Kok, Klaas, Bartenhagen, Christoph, Whelan, Christopher W., Palumbo, Orazio, Severgnini, Marco, Cifola, Ingrid, Dugas, Martin, Carella, Massimo, De Bellis, Gianluca, Rocchi, Mariano, Carbone, Lucia, Storlazzi, Clelia Tiziana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132716/ https://www.ncbi.nlm.nih.gov/pubmed/25034695 http://dx.doi.org/10.1093/nar/gku590

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