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Engineering modular and tunable genetic amplifiers for scaling transcriptional signals in cascaded gene networks

Synthetic biology aims to control and reprogram signal processing pathways within living cells so as to realize repurposed, beneficial applications. Here we report the design and construction of a set of modular and gain-tunable genetic amplifiers in Escherichia coli capable of amplifying a transcri...

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Detalles Bibliográficos
Autores principales: Wang, Baojun, Barahona, Mauricio, Buck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132719/
https://www.ncbi.nlm.nih.gov/pubmed/25030903
http://dx.doi.org/10.1093/nar/gku593