Acute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression

Hypoxia is associated with a variety of physiological and pathological conditions and elicits specific transcriptional responses. The elongation competence of RNA Polymerase II is regulated by the positive transcription elongation factor b (P-TEFb)-dependent phosphorylation of Ser2 residues on its C...

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Detalles Bibliográficos
Autores principales: Safronova, Olga S., Nakahama, Ken-Ichi, Morita, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132729/
https://www.ncbi.nlm.nih.gov/pubmed/25056306
http://dx.doi.org/10.1093/nar/gku611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132729/
https://www.ncbi.nlm.nih.gov/pubmed/25056306
http://dx.doi.org/10.1093/nar/gku611

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