Crystal structure of RNase H3–substrate complex reveals parallel evolution of RNA/DNA hybrid recognition

RNases H participate in the replication and maintenance of genomic DNA. RNase H1 cleaves the RNA strand of RNA/DNA hybrids, and RNase H2 in addition hydrolyzes the RNA residue of RNA–DNA junctions. RNase H3 is structurally closely related to RNases H2, but its biochemical properties are similar to t...

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Detalles Bibliográficos
Autores principales: Figiel, Małgorzata, Nowotny, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132731/
https://www.ncbi.nlm.nih.gov/pubmed/25016521
http://dx.doi.org/10.1093/nar/gku615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132731/
https://www.ncbi.nlm.nih.gov/pubmed/25016521
http://dx.doi.org/10.1093/nar/gku615

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