In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner

Co-localization of biochemical processes plays a key role in the directional control of metabolic fluxes toward specific products in cells. Here, we employ in vivo scaffolds made of RNA that can bind engineered proteins fused to specific RNA binding domains. This allows proteins to be co-localized o...

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Detalles Bibliográficos
Autores principales: Sachdeva, Gairik, Garg, Abhishek, Godding, David, Way, Jeffrey C., Silver, Pamela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132732/
https://www.ncbi.nlm.nih.gov/pubmed/25034694
http://dx.doi.org/10.1093/nar/gku617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132732/
https://www.ncbi.nlm.nih.gov/pubmed/25034694
http://dx.doi.org/10.1093/nar/gku617

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