Cargando…
In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner
Co-localization of biochemical processes plays a key role in the directional control of metabolic fluxes toward specific products in cells. Here, we employ in vivo scaffolds made of RNA that can bind engineered proteins fused to specific RNA binding domains. This allows proteins to be co-localized o...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132732/ https://www.ncbi.nlm.nih.gov/pubmed/25034694 http://dx.doi.org/10.1093/nar/gku617 |