Discovery of the β-barrel–type RNA methyltransferase responsible for N(6)-methylation of N(6)-threonylcarbamoyladenosine in tRNAs

Methylation is a versatile reaction involved in the synthesis and modification of biologically active molecules, including RNAs. N(6)-methyl-threonylcarbamoyl adenosine (m(6)t(6)A) is a post-transcriptional modification found at position 37 of tRNAs from bacteria, insect, plants, and mammals. Here,...

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Detalles Bibliográficos
Autores principales: Kimura, Satoshi, Miyauchi, Kenjyo, Ikeuchi, Yoshiho, Thiaville, Patrick C., de Crécy-Lagard, Valérie, Suzuki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132733/
https://www.ncbi.nlm.nih.gov/pubmed/25063302
http://dx.doi.org/10.1093/nar/gku618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132733/
https://www.ncbi.nlm.nih.gov/pubmed/25063302
http://dx.doi.org/10.1093/nar/gku618

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