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The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells

The Piwi-piRNA pathway is active in animal germ cells where its functions are required for germ cell maintenance and gamete differentiation. Piwi proteins and piRNAs have been detected outside germline tissue in multiple phyla, but activity of the pathway in mammalian somatic cells has been little e...

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Detalles Bibliográficos
Autores principales: Keam, Simon P., Young, Paul E., McCorkindale, Alexandra L., Dang, Thurston H.Y., Clancy, Jennifer L., Humphreys, David T., Preiss, Thomas, Hutvagner, Gyorgy, Martin, David I.K., Cropley, Jennifer E., Suter, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132735/
https://www.ncbi.nlm.nih.gov/pubmed/25038252
http://dx.doi.org/10.1093/nar/gku620