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CRISPR-Cas: an efficient tool for genome engineering of virulent bacteriophages
Bacteriophages are now widely recognized as major players in a wide variety of ecosystems. Novel genes are often identified in newly isolated phages as well as in environmental metavirome studies. Most of these novel viral genes have unknown functions but appear to be coding for small, non-structura...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132740/ https://www.ncbi.nlm.nih.gov/pubmed/25063295 http://dx.doi.org/10.1093/nar/gku628 |