Engineering self-contained DNA circuit for proximity recognition and localized signal amplification of target biomolecules

Biomolecular interactions have important cellular implications, however, a simple method for the sensing of such proximal events is lacking in the current molecular toolbox. We designed a dynamic DNA circuit capable of recognizing targets in close proximity to initiate a pre-programmed signal transd...

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Detalles Bibliográficos
Autores principales: Ang, Yan Shan, Yung, Lin-Yue Lanry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132759/
https://www.ncbi.nlm.nih.gov/pubmed/25056307
http://dx.doi.org/10.1093/nar/gku655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132759/
https://www.ncbi.nlm.nih.gov/pubmed/25056307
http://dx.doi.org/10.1093/nar/gku655

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