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Engineering self-contained DNA circuit for proximity recognition and localized signal amplification of target biomolecules
Biomolecular interactions have important cellular implications, however, a simple method for the sensing of such proximal events is lacking in the current molecular toolbox. We designed a dynamic DNA circuit capable of recognizing targets in close proximity to initiate a pre-programmed signal transd...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132759/ https://www.ncbi.nlm.nih.gov/pubmed/25056307 http://dx.doi.org/10.1093/nar/gku655 |