Cargando…

A Structural and Biochemical Model of Processive Chitin Synthesis

Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class. We identified the bacterial glycosyltransferase NodC as an appropriate model...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorfmueller, Helge C., Ferenbach, Andrew T., Borodkin, Vladimir S., van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132801/
https://www.ncbi.nlm.nih.gov/pubmed/24942743
http://dx.doi.org/10.1074/jbc.M114.563353