Cargando…

A Structural and Biochemical Model of Processive Chitin Synthesis

Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class. We identified the bacterial glycosyltransferase NodC as an appropriate model...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dorfmueller, Helge C., Ferenbach, Andrew T., Borodkin, Vladimir S., van Aalten, Daan M. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132801/ https://www.ncbi.nlm.nih.gov/pubmed/24942743 http://dx.doi.org/10.1074/jbc.M114.563353

Ejemplares similares

Effects of hypo-O-GlcNAcylation on Drosophila development
por: Mariappa, Daniel, et al.
Publicado: (2018)

The conserved threonine-rich region of the HCF-1(PRO) repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities
por: Kapuria, Vaibhav, et al.
Publicado: (2018)

O-GlcNAcase contributes to cognitive function in Drosophila
por: Muha, Villo, et al.
Publicado: (2020)

The Early Metazoan Trichoplax adhaerens Possesses a Functional O-GlcNAc System
por: Selvan, Nithya, et al.
Publicado: (2015)

2-Acylamido Analogues of N-Acetylglucosamine Prime Formation of Chitin Oligosaccharides by Yeast Chitin Synthase 2
por: Gyore, Jacob, et al.
Publicado: (2014)

Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-l-rhamnose biosynthesis in microalgae
por: Wagstaff, Ben A., et al.
Publicado: (2019)

A Refined Model for the TSG-6 Link Module in Complex with Hyaluronan: USE OF DEFINED OLIGOSACCHARIDES TO PROBE STRUCTURE AND FUNCTION
por: Higman, Victoria A., et al.
Publicado: (2014)

Monocyte-to-Macrophage Differentiation: SYNTHESIS AND SECRETION OF A COMPLEX EXTRACELLULAR MATRIX
por: Chang, Mary Y., et al.
Publicado: (2012)

Trimeric Structure of Langerin
por: Feinberg, Hadar, et al.
Publicado: (2010)

The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of α-1,3-galactosidic linkages in λ-carrageenan and blood group antigens
por: McGuire, Bailey E., et al.
Publicado: (2021)

Structural and compositional diversity of fibrillin microfibrils in human tissues
por: Eckersley, Alexander, et al.
Publicado: (2018)

Structure and Biosynthesis of Two Exopolysaccharides Produced by Lactobacillus johnsonii FI9785
por: Dertli, Enes, et al.
Publicado: (2013)

Heterogeneity of Collagen VI Microfibrils: STRUCTURAL ANALYSIS OF NON-COLLAGENOUS REGIONS
por: Maaß, Tobias, et al.
Publicado: (2016)

The Solution Structure of Heparan Sulfate Differs from That of Heparin: IMPLICATIONS FOR FUNCTION
por: Khan, Sanaullah, et al.
Publicado: (2013)

Structure of a Complex Phosphoglycan Epitope from gp72 of Trypanosoma cruzi
por: Allen, Simon, et al.
Publicado: (2013)

The Synthesis of UDP-N-acetylglucosamine Is Essential for Bloodstream Form Trypanosoma brucei in Vitro and in Vivo and UDP-N-acetylglucosamine Starvation Reveals a Hierarchy in Parasite Protein Glycosylation
por: Stokes, Matthew J., et al.
Publicado: (2008)

Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
por: Kanagawa, Mayumi, et al.
Publicado: (2014)

Identification of a Novel Family of Laminin N-terminal Alternate Splice Isoforms: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION
por: Hamill, Kevin J., et al.
Publicado: (2009)

Structural Analysis of Collagen Type I Interactions with Human Fibronectin Reveals a Cooperative Binding Mode
por: Erat, Michèle C., et al.
Publicado: (2013)

Functional binding of E-selectin to its ligands is enhanced by structural features beyond its lectin domain
por: Aleisa, Fajr A., et al.
Publicado: (2020)

Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence
por: Fontana, Carolina, et al.
Publicado: (2016)

Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes
por: Nonaka, Motohiro, et al.
Publicado: (2014)

Structural determinants in a glucose-containing lipopolysaccharide from Mycobacterium tuberculosis critical for inducing a subset of protective T cells
por: De, Prithwiraj, et al.
Publicado: (2018)

Structures of Complexes of a Metal-independent Glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-Acetylgalactosamine (UDP-GalNAc) and Its Hydrolysis Products
por: Pham, Tram T. K., et al.
Publicado: (2014)

Identification of Mono- and Disulfated N-Acetyl-lactosaminyl Oligosaccharide Structures as Epitopes Specifically Recognized by Humanized Monoclonal Antibody HMOCC-1 Raised against Ovarian Cancer
por: Shibata, Toshiaki K., et al.
Publicado: (2012)

Chemical Structure of Trichomonas vaginalis Surface Lipoglycan: A ROLE FOR SHORT GALACTOSE (β1–4/3) N-ACETYLGLUCOSAMINE REPEATS IN HOST CELL INTERACTION
por: Ryan, Christopher M., et al.
Publicado: (2011)

Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
por: Briggs, David C., et al.
Publicado: (2020)

Assembly of the Respiratory Mucin MUC5B: A NEW MODEL FOR A GEL-FORMING MUCIN
por: Ridley, Caroline, et al.
Publicado: (2014)

Immobilization of Heparan Sulfate on Electrospun Meshes to Support Embryonic Stem Cell Culture and Differentiation
por: Meade, Kate A., et al.
Publicado: (2013)

Post-assembly Modification of Bordetella bronchiseptica O Polysaccharide by a Novel Periplasmic Enzyme Encoded by wbmE
por: King, Jerry D., et al.
Publicado: (2009)

The Streptococcal Binding Site in the Gelatin-binding Domain of Fibronectin Is Consistent with a Non-linear Arrangement of Modules
por: Atkin, Kate E., et al.
Publicado: (2010)

Differential Regulation of Elastic Fiber Formation by Fibulin-4 and -5
por: Choudhury, Rawshan, et al.
Publicado: (2009)

Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium
por: Banerji, Suneale, et al.
Publicado: (2016)

Nidovirus Sialate-O-Acetylesterases: EVOLUTION AND SUBSTRATE SPECIFICITY OF CORONAVIRAL AND TOROVIRAL RECEPTOR-DESTROYING ENZYMES
por: Smits, Saskia L., et al.
Publicado: (2005)

Heparan Sulfate Inhibits Hematopoietic Stem and Progenitor Cell Migration and Engraftment in Mucopolysaccharidosis I
por: Watson, H. Angharad, et al.
Publicado: (2014)

Site-specific O-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by the Porphyromonas gingivalis Secreted Cysteine Protease (RgpB)
por: van der Post, Sjoerd, et al.
Publicado: (2013)

Fragments of Bacterial Endoglycosidase S and Immunoglobulin G Reveal Subdomains of Each That Contribute to Deglycosylation
por: Dixon, Emma V., et al.
Publicado: (2014)

Identification and Functional Characterization of a Highly Divergent N-Acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei
por: Damerow, Manuela, et al.
Publicado: (2014)

Glycosylation at Asn(211) Regulates the Activation State of the Discoidin Domain Receptor 1 (DDR1)
por: Fu, Hsueh-Liang, et al.
Publicado: (2014)

Sialyl-lactotetra, a Novel Cell Surface Marker of Undifferentiated Human Pluripotent Stem Cells
por: Barone, Angela, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7nupd71a0bkmu3tv7mt78r69ic