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A Coarse-Grained Model of Unstructured Single-Stranded DNA Derived from Atomistic Simulation and Single-Molecule Experiment

[Image: see text] A simple coarse-grained model of single-stranded DNA (ssDNA) was developed, featuring only two sites per nucleotide that represent the centers of mass of the backbone and sugar/base groups. In the model, the interactions between sites are described using tabulated bonded potentials...

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Detalles Bibliográficos
Autores principales: Maffeo, Christopher, Ngo, Thuy T. M., Ha, Taekjip, Aksimentiev, Aleksei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132850/
https://www.ncbi.nlm.nih.gov/pubmed/25136266
http://dx.doi.org/10.1021/ct500193u