Cargando…

Influence of Sequence and Covalent Modifications on Yeast tRNA Dynamics

[Image: see text] Modified nucleotides are prevalent in tRNA. Experimental studies reveal that these covalent modifications play an important role in tuning tRNA function. In this study, molecular dynamics (MD) simulations were used to investigate how modifications alter tRNA dynamics. The X-ray cry...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaoju, Walker, Ross C., Phizicky, Eric M., Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132867/
https://www.ncbi.nlm.nih.gov/pubmed/25136272
http://dx.doi.org/10.1021/ct500107y