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Prediction of miRNA-mRNA associations in Alzheimer’s disease mice using network topology

BACKGROUND: Little is known about the relationship between miRNA and mRNA expression in Alzheimer’s disease (AD) at early- or late-symptomatic stages. Sequence-based target prediction algorithms and anti-correlation profiles have been applied to predict miRNA targets using omics data, but this appro...

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Detalhes bibliográficos
Autores principales: Noh, Haneul, Park, Charny, Park, Soojun, Lee, Young Seek, Cho, Soo Young, Seo, Hyemyung
Formato: Online Artigo Texto
Idioma:English
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132902/
https://www.ncbi.nlm.nih.gov/pubmed/25086961
http://dx.doi.org/10.1186/1471-2164-15-644