Cargando…

Carboxylic Acids as A Traceless Activation Group for Conjugate Additions: A Three-Step Synthesis of (±)-Pregabalin

[Image: see text] The direct application of carboxylic acids as a traceless activation group for radical Michael additions has been accomplished via visible light-mediated photoredox catalysis. Photon-induced oxidation of a broad series of carboxylic acids, including hydrocarbon-substituted, α-oxy,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chu, Lingling, Ohta, Chisa, Zuo, Zhiwei, MacMillan, David W. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132975/
https://www.ncbi.nlm.nih.gov/pubmed/25032785
http://dx.doi.org/10.1021/ja505964r