Epigenetic Landscapes Explain Partially Reprogrammed Cells and Identify Key Reprogramming Genes

A common metaphor for describing development is a rugged “epigenetic landscape” where cell fates are represented as attracting valleys resulting from a complex regulatory network. Here, we introduce a framework for explicitly constructing epigenetic landscapes that combines genomic data with techniq...

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Detalles Bibliográficos
Autores principales: Lang, Alex H., Li, Hu, Collins, James J., Mehta, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133049/
https://www.ncbi.nlm.nih.gov/pubmed/25122086
http://dx.doi.org/10.1371/journal.pcbi.1003734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133049/
https://www.ncbi.nlm.nih.gov/pubmed/25122086
http://dx.doi.org/10.1371/journal.pcbi.1003734

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