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Epigenetic Landscapes Explain Partially Reprogrammed Cells and Identify Key Reprogramming Genes
A common metaphor for describing development is a rugged “epigenetic landscape” where cell fates are represented as attracting valleys resulting from a complex regulatory network. Here, we introduce a framework for explicitly constructing epigenetic landscapes that combines genomic data with techniq...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133049/ https://www.ncbi.nlm.nih.gov/pubmed/25122086 http://dx.doi.org/10.1371/journal.pcbi.1003734 |