5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulation

BACKGROUND: Recent mapping of 5-hydroxymethylcytosine (5hmC) provides a genome-wide view of the distribution of this important chromatin mark. However, the role of 5hmC in specific regulatory regions is not clear, especially at enhancers. RESULTS: We found a group of distal transcription factor bind...

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Detalles Bibliográficos
Autores principales: Choi, Inchan, Kim, Rinho, Lim, Hee-Woong, Kaestner, Klaus H, Won, Kyoung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133056/
https://www.ncbi.nlm.nih.gov/pubmed/25106691
http://dx.doi.org/10.1186/1471-2164-15-670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133056/
https://www.ncbi.nlm.nih.gov/pubmed/25106691
http://dx.doi.org/10.1186/1471-2164-15-670

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