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Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis

Cytokinesis terminates mitosis, resulting in separation of the two sister cells. Septins, a conserved family of GTP-binding cytoskeletal proteins, are an absolute requirement for cytokinesis in budding yeast. We demonstrate that septin-dependence of mammalian cytokinesis differs greatly between cell...

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Detalles Bibliográficos
Autores principales: Menon, Manoj B., Sawada, Akihiro, Chaturvedi, Anuhar, Mishra, Pooja, Schuster-Gossler, Karin, Galla, Melanie, Schambach, Axel, Gossler, Achim, Förster, Reinhold, Heuser, Michael, Kotlyarov, Alexey, Kinoshita, Makoto, Gaestel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133155/
https://www.ncbi.nlm.nih.gov/pubmed/25122120
http://dx.doi.org/10.1371/journal.pgen.1004558