Construction and Validation of a Regulatory Network for Pluripotency and Self-Renewal of Mouse Embryonic Stem Cells

A 30-node signed and directed network responsible for self-renewal and pluripotency of mouse embryonic stem cells (mESCs) was extracted from several ChIP-Seq and knockdown followed by expression prior studies. The underlying regulatory logic among network components was then learned using the initia...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Huilei, Ang, Yen-Sin, Sevilla, Ana, Lemischka, Ihor R., Ma'ayan, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133156/
https://www.ncbi.nlm.nih.gov/pubmed/25122140
http://dx.doi.org/10.1371/journal.pcbi.1003777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133156/
https://www.ncbi.nlm.nih.gov/pubmed/25122140
http://dx.doi.org/10.1371/journal.pcbi.1003777

Ejemplares similares