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Gearing up chromatin: A role for chromatin remodeling during the transcriptional restart upon DNA damage

During transcription, RNA polymerase may encounter DNA lesions, which causes stalling of transcription. To overcome the RNA polymerase blocking lesions, the transcribed strand is repaired by a dedicated repair mechanism, called transcription coupled nucleotide excision repair (TC-NER). After repair...

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Detalles Bibliográficos
Autores principales: Mandemaker, Imke K, Vermeulen, Wim, Marteijn, Jurgen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133215/
https://www.ncbi.nlm.nih.gov/pubmed/24809693
http://dx.doi.org/10.4161/nucl.29085