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Transcriptional Regulation of the Tumor Suppressor FHL2 by p53 in Human Kidney and Liver Cells

Four and a Half LIM protein 2 (FHL2) is a LIM domain only protein that is able to form various protein complexes and regulate gene transcription. Recent findings showed that FHL2 is a potential tumor suppressor gene that was down-regulated in hepatocellular carcinoma (HCC). Moreover, FHL2 can bind t...

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Detalles Bibliográficos
Autores principales: Xu, Jiaying, Zhou, Junwei, Li, Man-Shan, Ng, Chor-Fung, Ng, Yuen-Keng, Lai, Paul Bo-San, Tsui, Stephen Kwok-Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133229/
https://www.ncbi.nlm.nih.gov/pubmed/25121502
http://dx.doi.org/10.1371/journal.pone.0099359