Serotonin 5-HT(3) Receptor-Mediated Vomiting Occurs via the Activation of Ca(2+)/CaMKII-Dependent ERK1/2 Signaling in the Least Shrew (Cryptotis parva)

Stimulation of 5-HT(3) receptors (5-HT(3)Rs) by 2-methylserotonin (2-Me-5-HT), a selective 5-HT(3) receptor agonist, can induce vomiting. However, downstream signaling pathways for the induced emesis remain unknown. The 5-HT(3)R channel has high permeability to extracellular calcium (Ca(2+)) and upo...

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Detalles Bibliográficos
Autores principales: Zhong, Weixia, Hutchinson, Tarun E., Chebolu, Seetha, Darmani, Nissar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133232/
https://www.ncbi.nlm.nih.gov/pubmed/25121483
http://dx.doi.org/10.1371/journal.pone.0104718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133232/
https://www.ncbi.nlm.nih.gov/pubmed/25121483
http://dx.doi.org/10.1371/journal.pone.0104718

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