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Serotonin 5-HT(3) Receptor-Mediated Vomiting Occurs via the Activation of Ca(2+)/CaMKII-Dependent ERK1/2 Signaling in the Least Shrew (Cryptotis parva)
Stimulation of 5-HT(3) receptors (5-HT(3)Rs) by 2-methylserotonin (2-Me-5-HT), a selective 5-HT(3) receptor agonist, can induce vomiting. However, downstream signaling pathways for the induced emesis remain unknown. The 5-HT(3)R channel has high permeability to extracellular calcium (Ca(2+)) and upo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133232/ https://www.ncbi.nlm.nih.gov/pubmed/25121483 http://dx.doi.org/10.1371/journal.pone.0104718 |