Analysis of Mutant SOD1 Electrophoretic Mobility by Blue Native Gel Electrophoresis; Evidence for Soluble Multimeric Assemblies

Mutations in superoxide dismutase 1 (SOD1) cause familial forms of amyotrophic lateral sclerosis (fALS). Disease causing mutations have diverse consequences on the activity and half-life of the protein, ranging from complete inactivity and short half-life to full activity and long-half-life. Uniform...

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Detalles Bibliográficos
Autores principales: Brown, Hilda H., Borchelt, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133237/
https://www.ncbi.nlm.nih.gov/pubmed/25121776
http://dx.doi.org/10.1371/journal.pone.0104583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133237/
https://www.ncbi.nlm.nih.gov/pubmed/25121776
http://dx.doi.org/10.1371/journal.pone.0104583

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