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Increased Generation of HIV-1 gp120-Reactive CD8(+) T Cells by a DNA Vaccine Construct Encoding the Chemokine CCL3

DNA vaccines based on subunits from pathogens have several advantages over other vaccine strategies. DNA vaccines can easily be modified, they show good safety profiles, are stable and inexpensive to produce, and the immune response can be focused to the antigen of interest. However, the immunogenic...

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Detalles Bibliográficos
Autores principales: Øynebråten, Inger, Hinkula, Jorma, Fredriksen, Agnete B., Bogen, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133255/
https://www.ncbi.nlm.nih.gov/pubmed/25122197
http://dx.doi.org/10.1371/journal.pone.0104814