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Epidermal Growth Factor Stimulates Nuclear Factor-κB Activation and Heme Oxygenase-1 Expression via c-Src, NADPH Oxidase, PI3K, and Akt in Human Colon Cancer Cells

Previous report showed that epidermal growth factor (EGF) promotes tumor progression. Several studies demonstrated that growth factors can induce heme oxygenase (HO)-1 expression, protect against cellular injury and cancer cell proliferation. In this study, we investigated the involvement of the c-S...

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Detalles Bibliográficos
Autores principales: Lien, Gi-Shih, Wu, Ming-Shun, Bien, Mauo-Ying, Chen, Chien-Hsin, Lin, Chien-Huang, Chen, Bing-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133279/
https://www.ncbi.nlm.nih.gov/pubmed/25122478
http://dx.doi.org/10.1371/journal.pone.0104891