Cargando…

Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages

BACKGROUND: Inflammation triggered by infection or injury is tightly controlled by glucocorticoid hormones which signal via a dedicated transcription factor, the Glucocorticoid Receptor (GR), to regulate hundreds of genes. However, the hierarchy of transcriptional responses to GR activation and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Chinenov, Yurii, Coppo, Maddalena, Gupte, Rebecca, Sacta, Maria A, Rogatsky, Inez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133603/
https://www.ncbi.nlm.nih.gov/pubmed/25099603
http://dx.doi.org/10.1186/1471-2164-15-656