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Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages
BACKGROUND: Inflammation triggered by infection or injury is tightly controlled by glucocorticoid hormones which signal via a dedicated transcription factor, the Glucocorticoid Receptor (GR), to regulate hundreds of genes. However, the hierarchy of transcriptional responses to GR activation and the...
Autores principales: | Chinenov, Yurii, Coppo, Maddalena, Gupte, Rebecca, Sacta, Maria A, Rogatsky, Inez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133603/ https://www.ncbi.nlm.nih.gov/pubmed/25099603 http://dx.doi.org/10.1186/1471-2164-15-656 |
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