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Enhancing HMM-based protein profile-profile alignment with structural features and evolutionary coupling information

BACKGROUND: Protein sequence profile-profile alignment is an important approach to recognizing remote homologs and generating accurate pairwise alignments. It plays an important role in protein sequence database search, protein structure prediction, protein function prediction, and phylogenetic anal...

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Detalles Bibliográficos
Autores principales: Deng, Xin, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133609/
https://www.ncbi.nlm.nih.gov/pubmed/25062980
http://dx.doi.org/10.1186/1471-2105-15-252