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Enhancing HMM-based protein profile-profile alignment with structural features and evolutionary coupling information
BACKGROUND: Protein sequence profile-profile alignment is an important approach to recognizing remote homologs and generating accurate pairwise alignments. It plays an important role in protein sequence database search, protein structure prediction, protein function prediction, and phylogenetic anal...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133609/ https://www.ncbi.nlm.nih.gov/pubmed/25062980 http://dx.doi.org/10.1186/1471-2105-15-252 |