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ReformAlign: improved multiple sequence alignments using a profile-based meta-alignment approach

BACKGROUND: Obtaining an accurate sequence alignment is fundamental for consistently analyzing biological data. Although this problem may be efficiently solved when only two sequences are considered, the exact inference of the optimal alignment easily gets computationally intractable for the multipl...

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Detalles Bibliográficos
Autores principales: Lyras, Dimitrios P, Metzler, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133627/
https://www.ncbi.nlm.nih.gov/pubmed/25099134
http://dx.doi.org/10.1186/1471-2105-15-265