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ReformAlign: improved multiple sequence alignments using a profile-based meta-alignment approach
BACKGROUND: Obtaining an accurate sequence alignment is fundamental for consistently analyzing biological data. Although this problem may be efficiently solved when only two sequences are considered, the exact inference of the optimal alignment easily gets computationally intractable for the multipl...
Autores principales: | Lyras, Dimitrios P, Metzler, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133627/ https://www.ncbi.nlm.nih.gov/pubmed/25099134 http://dx.doi.org/10.1186/1471-2105-15-265 |
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