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Dynamic probabilistic threshold networks to infer signaling pathways from time-course perturbation data

BACKGROUND: Network inference deals with the reconstruction of molecular networks from experimental data. Given N molecular species, the challenge is to find the underlying network. Due to data limitations, this typically is an ill-posed problem, and requires the integration of prior biological know...

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Detalles Bibliográficos
Autores principales: Kiani, Narsis A, Kaderali, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133630/
https://www.ncbi.nlm.nih.gov/pubmed/25047753
http://dx.doi.org/10.1186/1471-2105-15-250