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Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

ABSTRACT: Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of inhibitory sialic acid-binding immuno...

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Detalles Bibliográficos
Autores principales: Chang, Yung-Chi, Olson, Joshua, Louie, Aaron, Crocker, Paul R., Varki, Ajit, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133643/
https://www.ncbi.nlm.nih.gov/pubmed/24788876
http://dx.doi.org/10.1007/s00109-014-1157-y