Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival

Parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of the substantia nigra. One of the genes linked with the onset of Parkinson's disease, DJ-1/PARK7, belongs to a novel glyoxalase family and influences mitochondrial activity. It has been assumed that glyo...

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Detalles Bibliográficos
Autores principales: Toyoda, Yusuke, Erkut, Cihan, Pan-Montojo, Francisco, Boland, Sebastian, Stewart, Martin P., Müller, Daniel J., Wurst, Wolfgang, Hyman, Anthony A., Kurzchalia, Teymuras V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133730/
https://www.ncbi.nlm.nih.gov/pubmed/25063200
http://dx.doi.org/10.1242/bio.20149399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133730/
https://www.ncbi.nlm.nih.gov/pubmed/25063200
http://dx.doi.org/10.1242/bio.20149399

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