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Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage

Kidney damage is markedly accelerated by high-salt (HS) intake in stroke-prone spontaneously hypertensive rats (SHRSP). Epoxyeicosatrienoic acids (EETs) are epoxygenase products of arachidonic acid which possess vasodepressor, natriuretic, and anti-inflammatory activities. We examined whether up-reg...

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Detalles Bibliográficos
Autores principales: Li, Jing, Stier, Charles T., Chander, Praveen N., Manthati, Vijay L., Falck, John R., Carroll, Mairéad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133783/
https://www.ncbi.nlm.nih.gov/pubmed/25177296
http://dx.doi.org/10.3389/fphar.2014.00187