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Structure and catalytic mechanism of human protein tyrosine phosphatome

Together with protein tyrosine kinases (PTKs), protein tyrosine phosphatases (PTPs) serve as hallmarks in cellular signal transduction by controlling the reversible phosphorylation of their substrates. The human genome is estimated to encode more than 100 PTPs, which can be divided into eleven sub-g...

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Detalles Bibliográficos
Autores principales: Kim, Seung Jun, Ryu, Seong Eon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133821/
https://www.ncbi.nlm.nih.gov/pubmed/23261054
http://dx.doi.org/10.5483/BMBRep.2012.45.12.240